Prof Hazel Screen
Professor of Biomedical Engineering
School of Engineering and Materials Science
Queen Mary University of London
h.r.c.screen@qmul.ac.ukQueen Mary University of London
www.sems.qmul.ac.uk/h.r.c.screen
Research
musculoskeletal, mechanobiology, organ-on-a-chip, matrix, tendon, joint
Interests
Hazel Screen is a Professor in Biomedical Engineering at QMUL, with a first degree in Mechanical Engineering, and an MRes in Instrumentation Systems. Since completing her PhD in tendon mechanics in 2003, she had maintained focus in this area, and now leads a research group with particular interests in natural structure-function behaviour in soft tissues and understanding injury mechanisms. Outside of work, she loves the great outdoors and spends a lot of time hiking and running. She is also a keen scuba diver, and loves to travel.Publications
2023
Zamboulis DE, Marr N, Lenzi L, Birch HL, Screen HRC, Clegg PD and Thorpe CT (2023). The Interfascicular Matrix of Energy Storing Tendons Houses Heterogenous Cell Populations Disproportionately Affected by Aging. 10.14336/AD.2023.0425-1Shivapatham G, Richards S, Bamber J, Screen H and Morrissey D (2023). Ultrasound Measurement of Local Deformation in the Human Free Achilles Tendon Produced by Dynamic Muscle-Induced Loading: A Systematic Review. 10.1016/j.ultrasmedbio.2023.03.014Waugh CM, Mousavizadeh R, Lee J, Screen HRC and Scott A (2023). Mild hypercholesterolemia impacts achilles sub-tendon mechanical properties in young rats. vol. 24, (1) 10.1186/s12891-023-06375-0Gains CC, Giannapoulos A, Zamboulis DE, Lopez-Tremoleda J and Screen HRC (2023). Development and application of a novel in vivo overload model of the Achilles tendon in rat. vol. 151, 10.1016/j.jbiomech.2023.111546Tayfur A, Şendil A, Sezik AÇ, Jean-François K, Sancho I, Le Sant G, Dönmez G, Duman M, Tayfur B, Pawson J, Uzlaşır S, Miller SC, Screen H and Morrissey D (2023). Self-reported bio-psycho-social factors partially distinguish patellar tendinopathy from other knee problems and explain patellar tendinopathy severity in jumping athletes: A case-control study. vol. 61, 57-65. 10.1016/j.ptsp.2023.02.009Waugh CM, Mousavizadeh R, Lee J, Screen HRC and Scott A (2023). The impact of mild hypercholesterolemia on injury repair in the rat patellar tendon. 10.1002/jor.25546Nolan J, Pearce OMT, Screen HRC, Knight MM and Verbruggen SW (2023). Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK. vol. 15, (3) 10.3390/cancers15030635Lake SP, Snedeker JG, Wang VM, Awad H, Screen HRC and Thomopoulos S (2023). Guidelines for ex vivo mechanical testing of tendon. 10.1002/jor.256472022
Candarlioglu PL, Dal Negro G, Hughes D, Balkwill F, Harris K, Screen H, Morgan H, David R, Beken S, Guenat O, Rowan W and Amour A (2022). Organ-on-a-chip: current gaps and future directions. vol. 50, (2) 665-673. 10.1042/BST20200661Tayfur A, Sendil A, Sezik AC, Jean-François K, Sancho I, Le Sant G, Donmez G, Duman M, Tayfur B, Pawson J, Uzlasir S, Miller SC, Screen H and Morrissey D (2022). Self-reported bio-psycho-social factors partially distinguish patellar tendinopathy from other knee problems and explain severity in jumping athletes: A case–control study. vol. 114, e105-e106. 10.1016/j.physio.2021.12.052Tayfur A, Zenner D, Miller SC, Screen H and Morrissey D (2022). Outcome predictors for recovery of patellar tendinopathy in jumping athletes: an international prospective cohort study. 10.1136/bmjsem-2022-sportskongres.9Tayfur A, Haque A, Salles JI, Malliaras P, Screen H and Morrissey D (2022). Are Landing Patterns in Jumping Athletes Associated with Patellar Tendinopathy? A Systematic Review with Evidence Gap Map and Meta-analysis. vol. 52, (1) 123-137. 10.1007/s40279-021-01550-62021
Zahradnik TM, Cresswell M, Squier K, Waugh C, Brunham L, Screen H and Scott A (2021). Can Achilles tendon xanthoma be distinguished from Achilles tendinopathy using Dixon method MRI? A cross-sectional exploratory study. vol. 22, (1) 10.1186/s12891-021-04494-0Patel D, Zamboulis DE, Spiesz EM, Birch HL, Clegg PD, Thorpe CT and Screen HRC (2021). Structure-function specialisation of the interfascicular matrix in the human achilles tendon. vol. 131, 381-390. 10.1016/j.actbio.2021.07.019Squier K, Scott A, Hunt MA, Brunham LR, Wilson DR, Screen H and Waugh CM (2021). The effects of cholesterol accumulation on Achilles tendon biomechanics: A crosssectional study. vol. 16, (9 September) 10.1371/journal.pone.0257269Waugh C, Mousavizadeh R, Screen H and Scott A (2021). The Impact of Hypercholesterolemia on Tendon Injury Repair. vol. 35, (S1) 10.1096/fasebj.2021.35.s1.02060Godinho MSC, Thorpe CT, Greenwald SE and Screen H (2021). Elastase treatment of tendon specifically impacts the mechanical properties of the interfascicular matrix. 10.1016/j.actbio.2021.01.0302020
Zamboulis D, Thorpe CT, Ashraf Kharaz Y, Birch HL, Clegg PD and Screen H (2020). Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix. 10.7554/eLife.58075Gains C, Correia J, Baan G, Noort W, Screen H and Maas H (2020). Force Transmission Between the Gastrocnemius and Soleus Sub-Tendons of the Achilles Tendon in Rat. vol. 8, 700-700. 10.3389/fbioe.2020.00700Tayfur A, Salles JI, Miller SC, Screen H and Morrissey D (2020). Patellar tendinopathy outcome predictors in jumping athletes: feasibility of measures for a cohort study. vol. 44, 75-84. 10.1016/j.ptsp.2020.05.004Shearer T, Parnell WJ, Lynch B, Screen HRC and Abrahams ID (2020). A recruitment model of tendon viscoelasticity that incorporates fibril creep and explains strain-dependent relaxation. vol. 142, (7) 10.1115/1.4045662Siebert T, Screen HRC and Rode C (2020). Computational modelling of muscle, tendon, and ligaments biomechanics. 10.1016/B978-0-12-819531-4.00008-02019
Chineye U, Jones E, Riley G, Morrissey D and Screen H (2019). An in vitro investigation into the effects of 10Hz cyclic loading on tenocyte metabolism. 10.1111/sms.13465Capilnasiu A, Hadjicharalambous M, Fovargue D, Patel D, Holub O, Bilston L, Screen H, Sinkus R and Nordsletten D (2019). Magnetic resonance elastography in nonlinear viscoelastic materials under load. vol. 18, (1) 111-135. 10.1007/s10237-018-1072-1Anssari-Benam A, Screen HRC and Bucchi A (2019). Insights into the micromechanics of stress-relaxation and creep behaviours in the aortic valve. vol. 93, 230-245. 10.1016/j.jmbbm.2019.02.0112018
Rowson DT, Shelton JC, Screen HRC and Knight MM (2018). Mechanical loading induces primary cilia disassembly in tendon cells via TGFβ and HDAC6. vol. 8, (1) 10.1038/s41598-018-29502-7Liu R, Becer CR and Screen HRC (2018). Guided Cell Attachment via Aligned Electrospinning of Glycopolymers. vol. 18, (12) 10.1002/mabi.201800293Cook JL and Screen HR (2018). Tendon pathology: Have we missed the first step in the development of pathology? 10.1152/japplphysiol.00002.2018Clegg P, Zamboulis D and Screen H (2018). Postnatal Development of the Functional Specialization of the Equine Superficial Digital Flexor Tendon. vol. 31, (S 02) a1-a25. 10.1055/s-0038-1668213PATEL D, Sharma S, SCREEN HRC and BRYANT S (2018). Effects of cell adhesion motif, fiber stiffness, and cyclic strain on tenocyte gene expression in a tendon mimetic fiber composite hydrogel. 10.1016/j.bbrc.2018.03.203Spiesz EM, Thorpe CT, Thurner PJ and Screen HRC (2018). Structure and collagen crimp patterns of functionally distinct equine tendons, revealed by quantitative polarised light microscopy (qPLM). vol. 70, 281-292. 10.1016/j.actbio.2018.01.0342017
Godinho MSC, Thorpe CT, Greenwald SE and Screen HRC (2017). Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing. vol. 7, (1) 10.1038/s41598-017-09995-4Shearer T, Thorpe CT, Spiesz E and SCREEN HRC (2017). The relative compliance of energy-storing tendons may be due to the helical fibril arrangement of their fascicles. 10.1098/rsif.2017.0261Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2017). Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons. vol. 56, 58-64. 10.1016/j.actbio.2017.03.024BECER CR, Screen HRC, Patel D and Liu R (2017). A2B-Miktoarm Glycopolymer Fibers and Their Interactions with Tenocytes. 10.1021/acs.bioconjchem.7b00279Patel D, Sharma S, Bryant SJ and Screen HRC (2017). Recapitulating the Micromechanical Behavior of Tension and Shear in a Biomimetic Hydrogel for Controlling Tenocyte Response. vol. 6, (4) 10.1002/adhm.201601095Elyasigomari V, Lee DA, Screen HRC and SHAHEED MH (2017). Development of a two-stage gene selection method that incorporates a novel hybrid approach using the cuckoo optimization algorithm and harmony search for cancer classification. vol. 67, (2017) 11-20. 10.1016/j.jbi.2017.01.016Anssari-Benam A, Bucchi A, SCREEN HRC and Evans SL (2017). A transverse isotropic viscoelastic constitutive model for aortic valve tissue. 10.1098/rsos.160585Gupta HS and Screen HRC (2017). Structural building blocks of soft tissues: Tendons and heart valves. 10.1007/978-3-319-45071-1_12016
Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2016). Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons. vol. 42, 308-315. 10.1016/j.actbio.2016.06.012Handsfield GG, Slane LC and Screen HRC (2016). Nomenclature of the tendon hierarchy: An overview of inconsistent terminology and a proposed size-based naming scheme with terminology for multi-muscle tendons. vol. 49, (13) 3122-3124. 10.1016/j.jbiomech.2016.06.028Mozdzen L, Thorpe S, SCREEN HRC and Harley B (2016). The effect of gradations in mineral content, matrix alignment, and applied strain on human mesenchymal stem cell morphology within collagen biomaterials. 10.1002/adhm.201600181Thorpe CT, Karunaseelan KJ, Ng Chieng Hin J, Riley GP, Birch HL, Clegg PD and Screen HRC (2016). Distribution of proteins within different compartments of tendon varies according to tendon type. vol. 229, (3) 450-458. 10.1111/joa.12485Rowson D, Knight MM and Screen HRC (2016). Zonal variation in primary cilia elongation correlates with localized biomechanical degradation in stress deprived tendon. vol. 34, (12) 2146-2153. 10.1002/jor.23229Chaudhry S, Fernando R, Screen H, Waugh C, Tucker A and Morrissey D (2016). The use of medical infrared thermography in the detection of tendinopathy: a systematic review. vol. 21, (2) 75-82. 10.1080/10833196.2016.1223575Thorpe CT, Peffers MJ, Simpson D, Halliwell E, Screen HRC and Clegg PD (2016). Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. vol. 6, 10.1038/srep20455Thorpe CT and Screen HRC (2016). Tendon structure and composition. vol. 920, 3-10. 10.1007/978-3-319-33943-6_1Godinho MSC, Screen HRC, Greenwald SE and Thorpe CT (2016). Elastin is more abundant in energy storing tendons and is localised to the tendon interfascicular matrix. vol. 97, (6) A3-A4. 2015
Thorpe CT, Godinho MSC, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons. vol. 52, 85-94. 10.1016/j.jmbbm.2015.04.009Thorpe CT, Chaudhry S, Lei II, Varone A, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation. vol. 25, (4) e381-e391. 10.1111/sms.12333Spiesz EM, Thorpe CT, Chaudhry S, Riley GP, Birch HL, Clegg PD and Screen HRC (2015). Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise. vol. 33, (6) 889-897. 10.1002/jor.22879Screen HRC, Berk DE, Kadler KE, Ramirez F and Young MF (2015). Tendon functional extracellular matrix. vol. 33, (6) 793-799. 10.1002/jor.22818Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). Eccentric and concentric exercise of the triceps surae: An in vivo study of dynamic muscle and tendon biomechanical parameters. vol. 31, (2) 69-78. 10.1123/JAB.2013-0284Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). Eccentric and Concentric Exercise of the Triceps Surae: An in Vivo Study of Dynamic Muscle and Tendon Biomechanical Parameters. vol. 31, (2) 69-78. 10.1123/JAB.2013-0284Mani-Babu S, Morrissey D, Waugh C, Screen H and Barton C (2015). The effectiveness of extracorporeal shock wave therapy in lower limb tendinopathy: a systematic review. vol. 43, (3) 752-761. 10.1177/0363546514531911Thorpe CT, Spiesz EM, Chaudhry S, Screen HRC and Clegg PD (2015). Science in brief: Recent advances into understanding tendon function and injury risk. vol. 47, (2) 137-140. 10.1111/evj.12346Chaudhry S, Morrissey D, Woledge RC, Bader DL and Screen HRC (2015). Eccentric and concentric exercise of the triceps surae: An in vivo study of dynamic muscle and tendon biomechanical parameters. vol. 31, (2) 69-78. 10.1123/JAB.2013-0284Waugh CM, Morrissey D, Jones E, Riley GP, Langberg H and Screen HRC (2015). In vivo biological response to extracorporeal shockwave therapy in human tendinopathy. vol. 29, 268-280. 10.22203/eCM.v029a20Elyasigomari V, Mirjafari MS, Screen HRC and Shaheed MH (2015). Cancer classification using a novel gene selection approach by meansof shuffling based on data clustering with optimization. vol. 35, (2015) 43-51. 10.1016/j.asoc.2015.06.015Thorpe CT, Birch HL, Clegg PD and Screen HRC (2015). Tendon Physiology and Mechanical Behavior: Structure-Function Relationships. 10.1016/B978-0-12-801590-2.00001-6Thorpe CT, Birch HL, Clegg PD and Screen HRC (2015). Chapter 1 Tendon Physiology and Mechanical Behavior Structure–Function Relationships. 10.1016/b978-0-12-801590-2.00001-62014
Shepherd JH, Riley GP and Screen HRC (2014). Early stage fatigue damage occurs in bovine tendon fascicles in the absence of changes in mechanics at either the gross or micro-structural level. vol. 38, 163-172. 10.1016/j.jmbbm.2014.06.005Peffers MJ, Thorpe CT, Collins JA, Eong R, Wei TKJ, Screen HRC and Clegg PD (2014). Proteomic analysis reveals age-related changes in tendon matrix composition, with age- and injury-specific matrix fragmentation. vol. 289, (37) 25867-25878. 10.1074/jbc.M114.566554Patel D, Bryant S, Riley G, Jones E and Screen H (2014). 78 Human Tenocyte Metabolism Under Pathological And Physiological Loading Conditions. vol. 48, (Suppl 2) a51-a51. 10.1136/bjsports-2014-094114.77Spiesz EM, Thorpe CT, Chaudhry S, Riley GP, Birch HL, Clegg PD and Screen HR (2014). 98 Early Inflammatory Response Of Tenocytes To Overload. vol. 48, (Suppl 2) a63-a64. 10.1136/bjsports-2014-094114.97Thorpe C, Peffers M, Simpson D, Halliwell E, Screen H and Clegg P (2014). 104 Characterisation Of The Proteome Of The Tendon Interfascicular Matrix. vol. 48, (Suppl 2) a68-a68. 10.1136/bjsports-2014-094114.103Rowson D, Knight M and Screen H (2014). 89 Primary Cilia In Tenocytes From The Inter-fascicular Matrix And The Fascicular Matrix. vol. 48, (Suppl 2) a58-a59. 10.1136/bjsports-2014-094114.88Morrissey D, Morton S, Anuj CA and Screen H (2014). Achillessehnentendinopathie. vol. 02, (03) 105-111. 10.1055/s-0034-1387914Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons. vol. 10, (7) 3217-3224. 10.1016/j.actbio.2014.04.008Waugh C, Jones E, Riley G, Langberg H, Morrissey D and Screen H (2014). The effects of extracorporeal shockwave therapy on matrix metalloprotease activity in tendinopathy (1046.8). vol. 28, (S1) 10.1096/fasebj.28.1_supplement.1046.8Thorpe CT, Riley GP, Birch HL, Clegg PD and Screen HRC (2014). Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading. vol. 11, (92) 10.1098/rsif.2013.1058Shepherd JH, Legerlotz K, Demirci T, Klemt C, Riley GP and Screen HRC (2014). Functionally distinct tendon fascicles exhibit different creep and stress relaxation behaviour. vol. 228, (1) 49-59. 10.1177/0954411913509977Smith R, McIlwraith W, Schweitzer R, Kadler K, Cook J, Caterson B, Dakin S, Heinegard D, Screen H, Stover S, Crevier-Denoix N, Clegg P, Collins M, Little C, Frisbie D, Kjaer M, van Weeren R, Werpy N, Denoix J-M, Carr A, Goldberg A, Bramlage L, Smith M and Nixon A (2014). Advances in the understanding of tendinopathies: A report on the Second Havemeyer Workshop on equine tendon disease. vol. 46, (1) 4-9. 10.1111/evj.121282013
Thorpe CT, Klemt C, Riley GP, Birch HL, Clegg PD and Screen HRC (2013). Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return. vol. 9, (8) 7948-7956. 10.1016/j.actbio.2013.05.004Thorpe CT, Birch HL, Clegg PD and Screen HRC (2013). The role of the non-collagenous matrix in tendon function. vol. 94, (4) 248-259. 10.1111/iep.12027Shepherd JH and Screen HRC (2013). Fatigue loading of tendon. vol. 94, (4) 260-270. 10.1111/iep.12037Legerlotz K, Riley GP and Screen HRC (2013). GAG depletion increases the stress-relaxation response of tendon fascicles, but does not influence recovery. vol. 9, (6) 6860-6866. 10.1016/j.actbio.2013.02.028Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2013). Response to letter to the editor: End effects in mechanical testing of biomaterials. vol. 46, (5) 10.1016/j.jbiomech.2012.12.020Legerlotz K, Jones GC, Screen HRC and Riley GP (2013). Cyclic loading of tendon fascicles using a novel fatigue loading system increases interleukin-6 expression by tenocytes. vol. 23, (1) 31-37. 10.1111/j.1600-0838.2011.01410.xThorpe CT, Udeze CP, Birch HL, Clegg PD and Screen HR (2013). Capacity for sliding between tendon fascicles decreases with ageing in injury prone equine tendons: a possible mechanism for age-related tendinopathy? vol. 25, 48-60. 10.22203/ecm.v025a04Screen HRC, Toorani S and Shelton JC (2013). Microstructural stress relaxation mechanics in functionally different tendons. vol. 35, (1) 96-102. 10.1016/j.medengphy.2012.04.004Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2013). Response to letter to the editor: End effects in mechanical testing of biomaterials. 10.1016/j.jbiomech.2012.12.020Thorpe CT, Klemt C, Riley GP, Birch HL, Clegg PD and Screen HRC (2013). Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return. vol. 9, (8) 7948-7956. 10.1016/j.actbio.2013.05.0042012
Thorpe CT, Udeze CP, Birch HL, Clegg PD and Screen HRC (2012). Specialization of tendon mechanical properties results from interfascicular differences. vol. 9, (76) 3108-3117. 10.1098/rsif.2012.0362Anssari-Benam A, Legerlotz K, Bader DL and Screen HRC (2012). On the specimen length dependency of tensile mechanical properties in soft tissues: gripping effects and the characteristic decay length. vol. 45, (14) 2481-2482. 10.1016/j.jbiomech.2012.07.016Screen HRC and Tanner KE (2012). Structure and Biomechanics of Biological Composites. 10.1002/9781118097298.weoc015Anssari-Benam A, Gupta HS and Screen HRC (2012). Strain transfer through the aortic valve. vol. 134, (6) 10.1115/1.4006812Morrissey D, Graham J, Screen H, Sinha A, Small C, Twycross-Lewis R and Woledge R (2012). Coronal plane hip muscle activation in football code athletes with chronic adductor groin strain injury during standing hip flexion. vol. 17, (2) 145-149. 10.1016/j.math.2011.12.003Screen HRC, Toorani S and Shelton JC (2012). Microstructural stress relaxation mechanics in functionally different tendons. 10.1016/j.medengphy.2012.04.004Legerlotz K, Jones ER, Screen HRC and Riley GP (2012). Increased expression of IL-6 family members in tendon pathology. vol. 51, (7) 1161-1165. 10.1093/rheumatology/kes0022011
Screen HRC, Seto J, Krauss S, Boesecke P and Gupta HS (2011). Extrafibrillar diffusion and intrafibrillar swelling at the nanoscale are associated with stress relaxation in the soft collagenous matrix tissue of tendons. vol. 7, (23) 11243-11251. 10.1039/c1sm05656eSimms C, Screen H and Evans S (2011). Nonlinearities in soft tissue strain. vol. 4, (8) 10.1016/j.jmbbm.2011.10.004Anssari-Benam A, Bader DL and Screen HRC (2011). Anisotropic time-dependant behaviour of the aortic valve. vol. 4, (8) 1603-1610. 10.1016/j.jmbbm.2011.02.010Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment. vol. 225, (8) 821-830. 10.1177/0954411911406340Morrissey D, Roskilly A, Twycross-Lewis R, Isinkaye T, Screen H, Woledge R and Bader D (2011). The effect of eccentric and concentric calf muscle training on Achilles tendon stiffness. vol. 25, (3) 238-247. 10.1177/0269215510382600Anssari-Benam A, Bader DL and Screen HRC (2011). A combined experimental and modelling approach to aortic valve viscoelasticity in tensile deformation. vol. 22, (2) 253-262. 10.1007/s10856-010-4210-6Sweeney E, Chaudhury S, Screen H, Woledge R, Bader D, Maffulli N and Morrissey D (2011). The effect of eccentric and concentric loading speed on the normal achilles tendon: an in vivo biomechanical study. vol. 45, (2) 10.1136/bjsm.2010.081554.25Chaudhry S, Screen HRC, Woledge RC, Bader D and Morrissey D (2011). The effect of loading speed on the force frequency spectrum during eccentric & concentric calf exercise. vol. 45, (2) 10.1136/bjsm.2010.081554.30Lewinsohn AD, Anssari-Benham A, Lee DA, Taylor PM, Chester AH, Yacoub MH and Screen HRC (2011). Anisotropic strain transfer through the aortic valve and its relevance to the cellular mechanical environment. vol. 225, (H8) 821-830. 10.1177/09544119114063402010
Legerlotz K, Riley GP and Screen HRC (2010). Specimen dimensions influence the measurement of material properties in tendon fascicles. vol. 43, (12) 2274-2280. 10.1016/j.jbiomech.2010.04.040Screen HRC, Byers S, Lynn AD, Nguyen V, Patel D and Bryant SJ (2010). Characterization of a novel fiber composite material for mechanotransduction research of fibrous connective tissues. vol. 20, (5) 738-747. 10.1002/adfm.200901711Gupta HS, Seto J, Krauss S, Boesecke P and Screen HRC (2010). In situ multi-level analysis of viscoelastic deformation mechanisms in tendon collagen. vol. 169, (2) 183-191. 10.1016/j.jsb.2009.10.0022009
Screen HRC and Evans SL (2009). Measuring strain distributions in the tendon using confocal microscopy and finite elements. vol. 44, (5) 327-335. 10.1243/03093247JSA491SCREEN H (2009). Hierarchical approaches to understanding tendon mechanics. vol. 4, (4) 481-499. 10.1299/jbse.4.4812008
Toorani S, Shelton JC and Screen HRC (2008). Characterizing structure-function relationships in tendon. vol. 2, Screen HRC (2008). Investigating load relaxation mechanics in tendon. vol. 1, (1) 51-58. 10.1016/j.jmbbm.2007.03.0022007
Cheng VWT and Screen HRC (2007). The micro-structural strain response of tendon. vol. 42, (21) 8957-8965. 10.1007/s10853-007-1653-3SCREEN HRC and Cheng VWT (2007). Strain mechanisms in tendon fascicles. vol. 21, 8957-8965. 10.1007/s10853-007-1653-32006
Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA and Shelton JC (2006). The influence of swelling and matrix degradation on the microstructural integrity of tendon. vol. 2, (5) 505-513. 10.1016/j.actbio.2006.05.0082005
Screen HRC, Bader DL, Shelton JC and Lee DA (2005). Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production. vol. 2005, 193-194. Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL and Lee DA (2005). The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles. vol. 33, (8) 1090-1099. 10.1007/s10439-005-5777-9Screen HRC, Shelton JC, Bader DL and Lee DA (2005). Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles. vol. 336, (2) 424-429. 10.1016/j.bbro.2005.08.102Sudre L, Cheung F, Kevorkian L, Young DA, Darrah C, Donell ST, Shepstone L, Porter S, Brockbank S, Edwards DR, Parker AE, Clark IM, Boubriak OA, Urban JPG, Cui Z, Tew SR, Li Y, Tweats LM, Hawkins RE, Hardingham TE, Green D, Partridge KA, Leveque I, Mann S, Oreffo ROC, Ball SG, Kielty CM, Qin M, Tai G and Polak JM (2005). British society for matrix biology autumn meeting. vol. 86, (3) 10.1111/j.0959-9673.2005.00426.x2004
Screen HRC, Bader DL, Lee DA and Shelton JC (2004). Local strain measurement within tendon. vol. 40, (4) 157-163. 10.1111/j.1475-1305.2004.00164.xScreen HRC, Lee DA, Bader DL and Shelton JC (2004). An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties. vol. 218, (2) 109-119. 10.1243/0954411043229840042003
Screen HRC, Lee DA, Bader DL and Shelton JC (2003). Development of a technique to determine strains in tendons using the cell nuclei. vol. 40, (1-3) 361-368. 2002
Screen HRC, Bader DL, Shelton JC and Lee DA (2002). Non-collagenous matrix components influence the micro-mechanical environment of tenocytes within tendon fascicles subjected to tensile strain. vol. 4, (SUPPL. 1) 41-42. BADER DL, Shelton JC, Lee DA and Screen HRC (2002). Development of a technique to determine strains in tendons using the cell nuclei. vol. 40, 361-368. Bader DL, Shelton JC, LEE DA and Screen HRC (2002). Non-collagenous matrix components influence the micro-mechanical environment of tenocytes within tendon fasciles subjected to tensile strain. vol. 4 suppl 1, 41-42. Grants
Grants of specific relevance to Tendon Research
Next generation organ-chip models - integrating 3D mechano-predictive environmentsScreen H and Bevan CM
Engineering and Physical Sciences Research Council (19-09-2022 - 30-03-2026)
PhD Studentship: Development of an arterial organ-chip to study the role of primary cilia in atherosclerosisKnight MM and Screen H
China Scholarship Council (06-09-2021 - 08-09-2025)
Development of an Organ-chip Model to examine Muscle DegenerationKnight MM, Screen H and Fazal MR
Engineering and Physical Sciences Research Council (19-09-2021 - 30-03-2025)
The interfascicular matrix niche - novel approaches to identify the aetiology of tendinopathyScreen H and Philbrooks LA
Engineering and Physical Sciences Research Council (20-09-2020 - 31-03-2024)
Queen Mary+Emulate Organs-on-chips CentreScreen HRC and Knight MM
£525,375 Emulate Inc and QMUL (20-09-2019 - 19-09-2023)
MICA: Organ-on-a-chip models for safety testing of regenerative medicine productsScreen HRC, Knight MM and El Haj A
£504,557 Medical Research Council (24-08-2020 - 23-08-2023)
PhD Studentship: Investigation of synovium-cartilage pro-inflammatory cross talk and the role of primary cilia using organ-chip modelsScreen HRC, Knight MM and Terrazas D
Conacyt Scholarship (16-09-2019 - 15-09-2022)
Modulating tendon micromechanics for injury prevention or managementScreen H and Gains C
Engineering and Physical Sciences Research Council (24-09-2017 - 29-09-2021)
Organ-on-a-chip TechnologiesScreen HRC, Bull AMJ, Haj AJE, Knight MM, Carr AJ, Gunn JPG, Dalby MJ and Workman P
£479,338 Medical Research Council (31-07-2018 - 30-07-2021)
Identifying the causes of age-related tendon injuryScreen HRC
£190,374 Dunhill Medical Trust (01-10-2018 - 31-03-2021)
Measuring local strain distributions through the equine SDFT as a novel indication of injury riskScreen HRC
£167,426 Horserace Betting Levy Board (01-04-2017 - 31-03-2019)
Post-natal development of the tendon inter-fascicular matrix for long-term tendon healthScreen HRC
Horserace Betting Levy Board (01-05-2015 - 30-04-2017)
The role of the inter-fascicular matrix in mediating tendon fatigue resistance: Do age related changes lead to tendinopathy?Screen H
£173,750 Versus Arthritis (01-10-2013 - 30-09-2016)
Role of the inter-fascicular matrix in age related deterioration of tendon mechanical functionScreen HRC
£290,208 Biotechnology and Biological Sciences Research Council (30-04-2013 - 29-06-2016)
The role of high frequency loading in the treatment of tendinopathy.Screen HRC
Orthopaedic Research UK (01-10-2012 - 30-09-2015)
Human tenocyte metabolism under physiological and pathological loading conditionsScreen H
£100,761 Versus Arthritis (03-10-2011 - 02-10-2014)
Human tenocyte metabolism under physiological & pathological loading.Screen HRC
Arthritis Research UK (01-09-2011 - 31-08-2014)
A Multidisciplinary investigation into the mechanics and biology of developing tendinopathy.Screen HRC and Riley GP
£192,438 Wellcome Trust (01-10-2009 - 31-01-2014)
Investigating aging in equine tendinopathy.Screen HRC
Horserace Betting Levy Board (01-05-2010 - 30-04-2013)
Extracorporeal Shock Wave Therapy for Achilles TendinopathyScreen HRC
EPSRC KTA (01-05-2011 - 30-04-2013)